Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 16.06
Human Site: S614 Identified Species: 27.18
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 S614 S L P T T A P S N S S S L T L
Chimpanzee Pan troglodytes XP_514658 769 86303 S614 S L P T T A P S N P S S L T L
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 S614 S L P T T A P S N S S S L T L
Dog Lupus familis XP_534424 883 97262 S797 S L P T N V L S S S S S L M V
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 P618 S L P T S V T P S S C G F T S
Rat Rattus norvegicus NP_001100006 704 79549 S618 S L P T S V P S S S S G F I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 F656 D L Q S E N I F T T S L L M I
Chicken Gallus gallus Q03237 686 77718 V597 C F K R T Q P V N F L S R S L
Frog Xenopus laevis P52551 743 82891 N642 A T P F K T E N G T F T N T D
Zebra Danio Brachydanio rerio NP_001003867 633 70853 N560 S C A V K E E N V L D Q G F I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 M609 I L G G E M S M K A L N E A F
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 A267 T S E A E E A A A N D W W L E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 L686 F S R L D V M L D E G D D C M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522 S251 L P S P T T S S I G D L D E F
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 93.3 100 60 N.A. 40 60 N.A. 20 33.3 13.3 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 100 73.3 N.A. 53.3 73.3 N.A. 40 40 40 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 0 N.A. 0 N.A. 13.3
P-Site Similarity: N.A. 20 N.A. 13.3 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 22 8 8 8 8 0 0 0 8 0 % A
% Cys: 8 8 0 0 0 0 0 0 0 0 8 0 0 8 0 % C
% Asp: 8 0 0 0 8 0 0 0 8 0 22 8 15 0 8 % D
% Glu: 0 0 8 0 22 15 15 0 0 8 0 0 8 8 8 % E
% Phe: 8 8 0 8 0 0 0 8 0 8 8 0 15 8 15 % F
% Gly: 0 0 8 8 0 0 0 0 8 8 8 15 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 8 0 0 0 0 8 15 % I
% Lys: 0 0 8 0 15 0 0 0 8 0 0 0 0 0 0 % K
% Leu: 8 58 0 8 0 0 8 8 0 8 15 15 36 8 36 % L
% Met: 0 0 0 0 0 8 8 8 0 0 0 0 0 15 8 % M
% Asn: 0 0 0 0 8 8 0 15 29 8 0 8 8 0 0 % N
% Pro: 0 8 50 8 0 0 36 8 0 8 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 8 8 0 0 0 0 0 0 0 0 8 0 0 % R
% Ser: 50 15 8 8 15 0 15 43 22 36 43 36 0 8 8 % S
% Thr: 8 8 0 43 36 15 8 0 8 15 0 8 0 36 0 % T
% Val: 0 0 0 8 0 29 0 8 8 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _